As
one of the world’s leading independent biomedical research
institutions, the Southwest Foundation for Biomedical Research
is dedicated to the advancement of human health through basic
research into the nature, causes, prevention and eradication
of disease. Leading this charge are some of the best and most
productive scientists in the nation. SFBR's staff of more than
70 doctoral-level scientists conducts nearly 180 research projects
in the departments of Genetics; Virology and Immunology; Physiology
and Medicine; Organic Chemistry; and Comparative Medicine. In
partnership with hundreds of researchers and institutions around
the world, SFBR scientists are working to defeat human suffering
caused by heart disease, diabetes, obesity, cancer, hypertension,
psychiatric disorders, diseases of the premature newborn, AIDS,
hepatitis, malaria, parasitic infections, and a host of other
infectious diseases.
SFBR's Department of Genetics works to advance human health through basic biomedical research with animal and human populations, specifically by characterizing the genetic components of susceptibility to common diseases of public health importance. Once the individual genes influencing a given disease are known, this genetic information can be used in drug development efforts to find more effective cures or methods of prevention for disease. The information can also be used to target available interventions to those individuals most likely to develop disease.
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Organic chemistry is the "central science" of biomedical research, providing a crucial bridge between biology and medicine. Organic chemistry and in particular organic synthesis is essential in such areas as drug discovery and development, investigations into the metabolic fate of natural and synthetic compounds, elucidation of biochemical pathways and the development of new techniques for clinical chemistry.
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Research in the Department of Physiology and Medicine at the Southwest Foundation attempts to answer basic questions about physiological mechanisms that regulate the progression of the most pervasive diseases in the United States: high blood pressure, atherosclerosis, high cholesterol, and cancer. Scientists hope that these answers will translate into treatments for the millions of people suffering from these chronic diseases.
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The Department of Virology and Immunology develops vaccines and therapeutics against viral pathogens, and determines how viruses replicate and spread through basic and applied research.
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