Department of Genetics Publications, 2002

Almasy, L. and MacCluer, J.W. Association studies of vascular phenotypes: How and why? Arterioscler. Thromb. Vasc. Biol. 22:1055-1057, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Arya, R., Blangero, J., Williams, K., Almasy, L., Dyer, T.D., Leach, R.J., O'Connell, P., Stern, M.P., and Duggirala, R. Factors of insulin resistance syndrome-related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic Mexican Americans. Diabetes 51:841-847, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Arya, R., Duggirala, R., Almasy, L., Rainwater, D.L., Mahaney, M.C., Cole, S., Dyer, T.D., Williams, K., Leach, R.J., Hixson, J.E., MacCluer, J.W., O'Connell, P, Stern, M.P., and Blangero, J. Linkage of high-density lipoprotein-cholesterol concentrations to a locus on chromosome 9p in Mexican Americans. Nat. Genet. 30:102-105, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Arya, R., Duggirala, D., Comuzzie, A.G., Puppala, S., Modem, S., Busi, B.R., and Crawford, M.H. Heritability of anthropometric phenotypes in caste populations of Visakhapatnam, India. Hum. Biol. 74:325-344, 2002. [Article Abstract]

Bella, J.N., MacCluer, J.W., Roman, M.J., Almasy, L., North, K.E., Welty, T.K., Lee, E.T., Fabsitz, R.R., Howard, B.V., and Devereux, R.B. Genetic influences on aortic root size in American Indians: The Strong Heart Study. Arterioscler. Thromb. Vasc. Biol. 22:1008-1011, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Bennett, A.B., Anderson, T.J.C., Barker, G.C., Michael, E., and Bundy, D.A.P. Sequence variation in the Trichuris trichiura ß-tubulin locus: Implications for the development of benzimidazole resistance. Int. J. Parasitol. 32:1519, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Bethony, J., Williams, J.T., Blangero, J., Kloos, H., Gazzinelli, A., Soares-Filho, B., Coelho, L., Alves-Fraga, L., Williams-Blangero, S., LoVerde, P.T., and Corrêa-Oliveira, R. Additive host genetic factors influence fecal egg excretion rates during Schistosoma mansoni infection in a rural area in Brazil. Am. J. Trop. Med. Hyg. 67:336-343, 2002. [Article Abstract] [Full Text Article in PDF]

Bierut, L.J., Saccone, N.L., Rice, J.P., Goate, A., Foroud, T, Edenberg, H., Almasy, L., Conneally, M., Crowe, R., Hesselbrock, V., Li, T.K., Nurnberger Jr., J., Porjesz, B., Schuckit, M.A., Tischfield, J., Begleiter, H., and Reich, T. Defining alcohol-related phenotypes in human. The Collaborative Study on the Genetics of Alcoholism. Alcohol Research and Health 26:208-213, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Bissler, J.J., Tsoras, M., Göring, H.H.H., Hug, P., Chuck, G., Tombragel, E., McGraw, C., Schlotman, J., Ralston, M.A., and Hug, G. Infantile dilated X-linked cardiomyopathy, G4.5 mutations, altered lipids, and ultrastructural malformations of mitochondria in heart, liver, and skeletal muscle. Lab. Invest. 82:335-344, 2002. [Article Abstract]

Broeckel, U., Hengstenberg, C., Mayer, B., Holmer, S., Martin, L.J., Comuzzie, A.G., Blangero, J., Nürnberg, P., Reis, A., Riegger, G.A.J., Jacob, H.J. and Schunkert, H. A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat. Genet. 30:210-214, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Chan, J., Robinson, E.S., Yeh, I.-T., and McCarrey, J.R. Absence of ras gene mutations in UV-induced malignant melanomas correlates with a dermal origin of melanomas correlates with a dermal origin of melanocytes in Monodelphis domestica. Cancer Letters 184:73-80, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Comuzzie, A.G. The emerging pattern of the genetic contribution to human obesity. Best Practice & Research Clin. Endocrinol. and Metab. 16:611-621, 2002. [Article Abstract]

Cox, L.A. The F1C1 gene: Structure and polymorphisms in baboon. J. Med. Primatol. 31:17-28, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Cox, L.A., Birnbaum, S., and VandeBerg, J.L. Identification of candidate genes regulating HDL cholesterol using a chromosomal region expression array. Genome Res. 12:1693-1702, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Crystal, R.G., Bitterman, P.B., Mossman, B., Schwarz, M.I., Sheppard, D., Almasy, L., Chapman, H.A., Friedman, S.L., King, Jr., T.E., Leinwand, L.A., Liotta, L., Martin, G.R., Schwartz, D.A., Schultz, G.S., Wagner, C.R., and Musson, R.A. Future research directions in idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 166:236-246, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Deng, H.-W., Mahaney, M.C., Williams, J.T., Li, J., Conway, T., Davies, K.M., Li, J.-L., Deng, H., and Recker, R.R. Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases. Genet. Epidemiol. 22:12-25, 2002. [Article Abstract] [Full Text Article in PDF]

Duarte, N., Wang, X.L., and Wilcken, D.E.L. Effects of anticoagulant and time of plasma separation on measurement of homocysteine. Clin. Chem. 48(4):665-668, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Duggirala, R., Uttley, M., Williams, K., Arya, R., Blangero, J., and Crawford, M.H. Genetic determination of biological age in the mennonites of the midwestern United States. Genet. Epidemiol. 23:97-109, 2002. [Article Abstract] [Full Text Article in PDF]

Ferreira, M.U., Nair, S., Van Hyunh, T., Kawamoto, F., and Anderson, T.J.C. Microsatellite characterization of Plasmodium falciparum from cerebral and uncomplicated malaria patients in Southern Vietnam. J. Clin. Microbiol. 40:1854-1857, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Fu, W.Y., Dudman, N.P.B., Perry, M.A., and Wang, X.L. Homocysteine attenuates hemodynamic responses to nitric oxide in vivo. Atherosclerosis 161:169-176, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Fu, W.Y., Dudman, N.P.B., Perry, M.A., and Wang, X.L. Leukocytes extravasation in acute homocysteinemic rats. Atherosclerosis 161:177-183, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Ha, J.C., Robinette, L., Almasy, L., and Dyke, B. Genetics and caging type affect birth weight in captive pigtailed macaques (Macaca nemestrina). Am. J. Primatol. 56:207-213, 2002. [Article Abstract] [Full Text Article in PDF]

Hlusko, L.J., Weiss, K.M., and Mahaney, M.C. Statistical genetic comparison of two techniques for assessing molar crown size in pedigreed baboons. Am. J. Phys. Anthropol. 117:182-189. [Article Abstract] [Full Text Article in PDF]

Hunt, K.J., Duggirala, R., Göring, H.H., Williams, J.T., Almasy, L., Blangero, J., O'Leary, D.H., and Stern, M.P. Genetic basis of variation in carotid artery plaque in the San Antonio Family Heart Study. Stroke 33:2775-2780, 2003. [Article Abstract] [Full Text Article in PDF / Full Text Document in HTML]

Kammerer, C.M., Rainwater, D.L., Cox, L.A., Schneider, J.L., Mahaney, M.C., Rogers, J., and VandeBerg, J.L. Locus controlling LDL cholesterol response to dietary cholesterol is on baboon homologue of human chromosome 6. Arterioscler. Thromb. Vasc. Biol. 22:1720-1725, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Kushwaha, R.S., VandeBerg, J.F., Jackson, E.M., and VandeBerg, J.L. High and low responding strains of laboratory opossums differ in sterol 27-hydroxylase and acyl-coenzyme A: Cholestero-acyltransferase activities on a high cholesterol diet. J. Nutr. Biochem. 12:664-673, 2001. [Article Abstract]

Le Saux, O., Beck, K., Sachsinger, C., Treiber, C., Göring, H.H.H., Curry, K., Johnson, E.W., Bercovitch, L., Marais, A.-S., Terry, S.F., Viljoen, D.L., and Boyd, C.D. Evidence for a founder effect for pseudoxanthoma elasticum in the Afrikaner population of South Africa. Hum. Genet. 111:331-338, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Martin, L.J., Cole, S.A., Hixson, J.E., Mahaney, M.C., Czerwinski, S.A., Almasy, L., Blangero, J., and Comuzzie, A.G. Genotype by smoking interaction for leptin levels in the San Antonio Family Heart Study. Genet. Epidemiol. 22:105-115, 2002. [Article Abstract] [Full Text Article in PDF]

Martin, L.J., Comuzzie, A.G., Dupont, S., Vionnet, N., Dina, C., Gallina, S., Houari, M., Blangero, J., and Froguel, P. A quantitative trait locus influencing type 2 diabetes susceptibility maps to a region on 5q in an extended French family. Diabetes 51:3568-3572, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Martin, L.J., Mahaney, M.C., Almasy, L., Hixson, J.E., Cole, S.A., MacCluer, J.W., Jaquish, C.E., Blangero, J., and Comuzzie, A.G. A quantitative trait locus on chromosome 22 for serum leptin levels adjusted for serum testosterone. Obes. Res. 10:602-607, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Martin, L.J., Mahaney, M.C., Almasy, L., MacCluer, J.W., Blangero, J., Jaquish, C.E. and Comuzzie, A.G. Leptin's sexual dimorphism results from genotype by sex interactions mediated by testosterone. Obes. Res. 10:14-21, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Martin, L.J., Mahaney, M.C., Bronikowski, A., Carey, K.D., Dyke, B., and Comuzzie, A.G. Lifespan in captive baboons is heritable. Mech. Ageing Dev. 123:1461-1467, 2002. [Article Abstract]

Matvienko, O.A., Lewis, D.S., Swanson, M., Arndt, B., Rainwater, D.L., Stewart, J., and Alekel, D.L. A single daily dose of soybean phytosterols in ground beef decreases serum total cholesterol and LDL cholesterol in young, mildly hypercholesterolemic men. Am. J. Clin. Nutr 76:57-64, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

McDonald, S.P., Hoy, W.E., Maguire, G.P., Duarte, N.L., Wilcken, D.E.L., and Wang, X.L. The p53Pro72Arg polymorphism is associated with albuminuria among Aboriginal Australians. J. Am. Soc. Nephrol. 13:677-683, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Merikangas, K., Chakravarti, A., Moldin, S., Araj, H., Blangero, J., Burmeister, M., Crabbe, J., DePaulo, R., Foulks, E., Freimer, N., Koretz, D., Lichtenstein, W., Mignot, E., Reiss, A., Risch, N., and Takahashi, J. Future of genetics of mood disorders research. Biol. Psychiatry 52:457-477, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Morris, B.J., Markus, M.A., Glenn, C.L., Adams, D.J., Colagiuri, S., and Wang, X.L. Association of a functional inducible nitric oxide synthase promoter variant with complications in type 2 diabetes. J. Mol. Med. 80-:96-104, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Nakeeb, A, Comuzzie, A.G., Martin, L., Sonnenberg, G.E., Swartz-Basile, D., Kissebah, A.H., and Pitt, H.A. Gallstones: genetics versus environment. Ann. Surg. 235:842-849, 2002. [Article Abstract]

Nair, S., Brockman, A., Paiphun, L., Nosten, F. and Anderson, T.J.C. Rapid genotyping of loci involved in antifolate drug resistance in Plasmodium falciparum by primer extension. Intl. J. Parasitol. 32:852-858, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Newman, T.K., Fairbanks, L.A., Pollack, D., and Rogers, J. Effectiveness of a human microsatellite loci for assessing paternity in a captive colony of vervets (Chlorocebus aethiops sabaeus). Am. J. Primatol. 56:237-243, 2002. [Article Abstract] [Full Text Article in PDF]

North, K.E., MacCluer, J.W., Devereux, R.B., Howard, B.V., Welty, T.K., Best, L.G., Lee, E.T., Fabsitz, R.R., and Roman, M.J. Heritability of carotid artery structure and function: The Strong Heart Family Study. Arterioscler. Thromb. Vasc. Biol. 22:1698-1703, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Porjesz, B., Almasy, L., Edenberg, H.J., Wang, K., Chorlian, D.B., Foroud, T., Goate, A., Rice, J.P., O'Connor, S.J., Rohrbaugh, J., Kuperman S., Bauer, L.O., Crowe, R.R., Schuckit, M.A., Hesselbrock, V., Conneally, P.M., Tischfield, J.A. Li, T.-K., Reich, T., and Begleiter, H. Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc. Natl. Acad. Sci. 99:3729-3733, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Porjesz, B., Begleiter, H., Wang, K., Almasy, L., Chorlian, D.B., Stimus, A.T., Kuperman, S., O'Connor, S.J., Rohrbaugh, J., Bauer, L.O., Edenberg, H.J., Goate, A., Rice, J.P., and Reich, T. Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes. Biolog. Psychol. 61:229-248, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Rainwater, D.L., Kammerer, C.M., Carey, K.D., Dyke, B., VandeBerg, J.F., Shelledy, W.R., Moore, P.H., Jr., Mahaney, M.C., McGill, H.C., Jr., and VandeBerg, J.L. Genetic determination of HDL variation and response to diet in baboons. Atherosclerosis 161:335-343, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Rainwater, C.L., Kammerer, C.M., Cox, L.A., Rogers, J., Carey, K.D., Dyke, B., Mahaney, M.C., McGill, H.C., Jr., and VandeBerg, J.L. A major gene influences variation in large HDL particles and their response to diet in baboons. Atherosclerosis 163:241-248, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Reynolds, J., Gouin, N., Pain, S., Grandjean, F., Demers, A., and Souty-Grosset, C. Irish crayfish populations: Ecological and preliminary genetical findings. In: Freshwater Crayfish XIII,. G.J. Whisson and B. Pott, (eds.) pp. 584-594, 2002. Rohr, C.J.B., Ranson, H., Wang, X., and Besansky, N.J. Structure and evolution of mtanga, a retrotransposon actively expressed on the Y chromosome of the Africian malaria vector Anopheles gambiae. Mol. Biol. Evol. 19(2):149-162, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Ross, J.L., Laston, S., Pelto, P.J., and Muna, L. Exploring explanatory models of women's reproductive health in rural Bangladesh. Cult. Health Sex 4:173-190, 2002. [Article Abstract]

Saccone, N.L., Rice, J.P., Rochberg, N., Williams, J.T., Goate, A., Reich, T., Edenberg, H.J., Foroud, T., Nurnberger, J.I., Jr., Bierut, L.J., Crowe, R., and Li, T.-K. Linkage for platelet monoamine oxidase (MAO) activity: Results from a replication sample. Alcohol Clin. Exp. Res. 26:603-609, 2002. [Article Abstract]

Sachdev, P.S., Valenzuela, M., Wang, X.L., Looi, J.C.L., and Brodaty, H. Relationship between plasma homocysteine levels and brain atrophy in healthy elderly individuals. Neurology 58:1539-1541, 2002. [Article Abstract]

Soria, J.M., Almasy, L., Souto, J.C., Bacq, D., Buil, A., Faure, A., Martinez-Marchán, E., Mateo, J., Borrell, M., Stone, W., Lathrop, M., Fontcuberta, J., and Blangero, J. A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease. Am. J. Hum. Genet. 70:567-574, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Soria, J.M., Blangero, J., Souto, J.C., Martínez-Sánchez, E., Martínez-Marchán, E., Coll, I., Tirado, I., Cercós, A., Almasy, L., and Fontcuberta, J. Identification of a large deletion and three novel mutations in exon 13 of the factor V gene in a Spanish family with normal factor V coagulant and anticoagulant properties. Hum. Genet. 111:59-65, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Souto, J.C., Almasy, L., Borrell, M., Stone, W.H., Blanco-Vaca, F., Soria, J.M., Blangero, J., and Fontcuberta, J. Thromboplastin-thrombomodulin-mediated time and serum folate levels are genetically correlated with the risk of thromboembolic disease: Results from the GAIT Project. Thromb. Haemost. 87:68-73, 2002. [Article Abstract] [Full Text Article in PDF]

Stidley, C.A., Shah, V.O., Narva, A.S., Dalton, D., MacCluer, J.W., Bobelu, A., Scavini, M., Welty, T.K., and Zager, P.G. A population-based, cross-sectional survey of the Zuni Pueblo: A collaborative approach to an epidemic of kidney disease. Am. J. Kidney Disease 39:358-368, 2002. [Article Abstract] [Full Text Article in PDF] [Full Text Article in HTML]

Terwilliger, J.D., Göring, H.H.H., Magnusson, P.K.E., and Lee, J.H. Study design for genetic epidemiology and gene mapping: The Korean Diaspora Project. Shengming Kexue Yanjiu, Life Sci. Res. 6:95-115, 2002.

Terwilliger, J.D., Haghighi, F., Hiekkalinna, T.S., and Göring, H.H.H. A bias-ed assessment of the use of SNPs in human complex traits. Curr. Opin. Gen. Devel. 12:726-734, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Thomas, P.S., Bruce, C., Birkhead, A., and Wang, X.L. Effect of ecNOS polymorphisms and coronary artery disease upon exhaled nitric oxide. J. Mol. Med. 80:181-186, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

VandeBerg, J.L. and Stone, W.H. The future of animal research. ILAR J. 43:110-113, 2002.

Wang, J., Dudley, D., and Wang, X.L. Haplotype specific effects on endothelial NO synthase promoter efficiency. Arterioscler. Thromb. Vasc. Biol. 22:e1-4, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Wang, X.L., Greco, M., Sim, A.S., Duarte, N., Wang, J., and Wilcken, D.E.L. Effect of CYP1A1 MspI polymorphism on cigarette smoking related coronary artery disease and diabetes. Atheroclerosis 162:391-397, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Wang, X.L., Greco, M., Sim, A.S., Duarte, N., Wang, J., and Wilcken, D.E.L. Glutathione S-transferase mu1 deficiency, cigarette smoking and coronary artery disease. J. Cardiovasc. Risk, 9:25-31, 2002. [Article Abstract]

Wang, X.L., Wang, J., and Rainwater, D.L. Acute effects of insulin-like growth factor-1 on Lp(a) levels in baboons. Metabolism 51(4):508-513, 2002. [Article Abstract] [Full Text Article in PDF]

Williams-Blangero, S. and Blangero, J. Human host susceptibility to intestinal worm infections. In: World Class Parasites: Ascaris, Trichuris, and Hookworm. C. Holland and M. Kennedy (eds.), Kluwer, New York, pp 167-184, 2002.

Williams-Blangero, S., McGarvey, S.T., Subedi, J., Wiest, P.M., Upadhayay, R.P., Rai, D.R., Jha, B., Olds, G.R., Guanling, W., and Blangero, J. Genetic component to susceptibility to Trichuris trichiura: Evidence from two Asian populations. Genet. Epidemiol. 22:254-264, 2002. [Article Abstract] [Full Text Article in PDF]

Williams-Blangero, S., Towne, B., Subedi, J., and Blangero, J. Genetic studies of the Jirels: From population genetics to genetic epidemiology. In: Halfway to the Mountain: The Jirels of Eastern Nepal. Kathmandu: Tribhuvan University Press, pp 170-183, 2002.

Williams-Blangero, S., VandeBerg, J.L., and Dyke, B. Genetic management of nonhuman primates. J. Med. Primatol. 31:1-7, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]

Williams-Blangero, S., VandeBerg, J.L., Subedi, J., Aivaliotis, M.J., Rai, D.R., Upadhayay, R.P., Jha, B., and Blangero, J. Genes on chromosomes 1 and 13 have significant effects on Ascaris infection. Proc. Natl. Acad. Sci. U.S.A. 99:5533-5538, 2002. [Article Abstract] [Full Text Article in PDF / Full Text Article in HTML]