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Research in the Department of Physiology and Medicine at the Southwest Foundation attempts to answer basic questions about physiological mechanisms that regulate the progression of the most pervasive diseases in the United States: high blood pressure, atherosclerosis, high cholesterol, and cancer. Scientists hope that these answers will translate into treatments for the millions of people suffering from these chronic diseases.

Specific programs study the effects of cholesteryl ester transfer protein activity on low and high density lipoprotein cholesterol levels; the risk factors associated with development of atherosclerosis in young persons; the neural mechanisms that contribute to blood pressure regulation and the neuroendocrine factors that influence salt and water intake behavior; and the search for novel compounds to fight cancer.

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» Drug Discovery Program
We conduct a Drug Discovery Program aimed at the discovery of new anticancer agents by both mechanism-based screening and mechanism-blind screening.

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